24 results about "Drug delivery" patented technology

A drug delivery monitoring system comprising a monitor is disclosed that utilizes sound to monitor the occurrence and properties of a drug delivery event. The monitor is affixed to the exterior of a drug delivery device or drug container, and thus does not require disassembly of the drug delivery device and cannot interfere with the operation of the drug delivery device. The monitoring system includes a display device such as a smart phone or tablet computer for analyzing data related to the drug delivery device usage and displaying information to a patient or caregiver before, during, and after a drug delivery event.

Methods and apparatus for improving administration of drugs through the use of heat and other physical means. The present invention relates to the use of heat and other physical means in conjunction with specially designed dermal drug delivery systems, conventional commercial dermal drug delivery systems, or drugs delivered into a sub-skin depot site via injection and other methods to alter, mainly increase, the drug release rate from the dermal drug delivery systems or the depot sites to accommodate certain clinical needs.

Pharmaceutical composition comprising micro particles having an average diameter ranging from 40 to 150 nm, consisting of one or more lipids, a drug and, optionally, a steric stabilizer, suitable to the transmucosal passage and to the overcoming of the blood-brain barrier and the blood-cerebrospinal fluid barrier, said micro particles being obtained dispersing in an aqueous medium cooled to 2-4° C. an oil/water or a water/oil/water micro emulsion comprising said constituents.

Some embodiments of a medication delivery system provides for the recommendation or delivery of an amount of medication to a patient based on physiological parameter information and a set or rules. Some embodiments provide for systems and methods of medication delivery based on physiological parameters of, a patient, such as blood glucose level, blood pressure, and the like.

The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.

An implantable medical device including an implantable elongate component and at least one elongate drug-delivery element. The elongate drug-delivery element releasably carries at least one drug and is configured to be mounted to the elongate component such that the longitudinal axis of the drug-delivery element is substantially parallel with a longitudinal axis of the elongate component.

The present invention relates to a method for determining start timing of supply of drug to be given in which a peripheral circulatory function and an autonomic nervous function are activated through a stimulus applied to a stimulus application origin part of a body surface by an acupuncture needle or warm heating etc., and a drug conveyance system according to the method for determining start timing of supply of drug.

Novel acoustically sensitive drug carrying particles comprising low concentrations of phosphatidylethanolamine are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.

A radiation delivery source, such as a stent, and method for making radioactive a delivery source are disclosed. A drug delivery source and method for making a drug delivery region on the drug delivery source are also disclosed.

The invention discloses a wet packing agent for treating rheumatoid bone bi-syndrome and a preparation method thereof. The wet packing agent comprises raw common monkshood mother root, raw arisaema root, clematis root, earthworm, zedoary, Szechuan lovage rhizome and Chinese angelica and is prepared by the percolation method. The wet packing agent can be matched with a dual-force air pressure sealing treatment instrument with the transdermal drug delivery way for drug administration on the focus site, and is characterized by high efficacy, short treatment course, safety and reliability to the rheumatoid bone bi-syndrome; furthermore, clinical trails prove that the total effective rate for patients with lumbar intervertebral disc extrusion accompanied with different degrees of spinal stenosis is 98.5%.

The invention discloses a new method for functional modification of poly(beta-pinene) resin, and particularly relates to a new method for carrying out functional modification on poly(beta-pinene)resin through a sulfydryl-double bond addition reaction. The method includes the steps that a photoinitiator is adopted to initiate the addition reaction of double bonds on poly(beta-pinene) molecular chains and a sulfhydryl compound, polar functional groups carried by the sulfhydryl compound are introduced onto the poly(beta-pinene) molecular chains, and functionally-modified poly(beta-pinene)resin is obtained. Due to the introduction of the polar functional groups, on one hand, the compatibility of poly(beta-pinene) and common polyacrylic resin can be improved, and thus the tackifying effect of poly(beta-pinene) on polyacrylic resin can be improved; on the other hand, the traditional polymer poly(beta-pinene) can be endowed with new functions, the application field of the terpene polymer can be widened, and efficient utilization of the natural resource beta-pinene can be promoted; for example, after beta-pinene is modified with mercaptopropionic acid or mercaptoacetic acid, a product can be self-emulsified in water to form nano-particles and is expected to be applied to drug delivery systems.

Disclosed herein are processes for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc., which are useful in drug delivery applications.

The invention discloses a novel rectal administration device, comprising a drug delivery tube main body, a support plate, a connector, a push rod, a push disc, an insertion tube and an expansion sleeve, wherein support plate is arranged on the left side of the drug delivery tube main body; the connector is arranged on the right side of the drug delivery tube main body; the insertion pipe is arranged on the connector and is sleeved with the expansion sleeve; the push rod is arranged in the drug delivery tube main body; the push disc is arranged at the left end of the push rod; and a piston is arranged on the right end of the push rod. Compared with the prior art, the novel rectal administration device of the invention is simple in structure, reasonable in design and convenient to use, and allows liquid or solid medicines to be conveniently and rapidly fed to the rectal focus of a patient, so the novel rectal administration device replaces fingers to feed suppositories into the rectum ofthe patient, and organ injuries and bacterial infection are avoided; and thus, the novel rectal administration device is worthy of promotion.

The invention relates to the technical field of biomedical materials, and particularly discloses a multifunctional polyurea acid derivative, a preparation method thereof and application of the multifunctional polyurea acid derivative in a fluorescent probe and a drug delivery system. The invention provides a polyureido acid derivative, the molecular structural formula of the polyureido acid derivative comprises a structure as shown in formula I: wherein R and R'represent amino acid residues; x = O or S; y = NH, O, C or S, and Z = NH, O or S; n is equal to 2 to 200.

The invention relates to a packaging machine for the pharmaceutical industry, in particular to an automatic counting packaging machine for medicine packaging. The automatic counting packaging machine comprises a rack, a drive device and a counting device. Medicines pass through a finished medicine conveying mechanism, the number of packaging formed products is inducted through an induction head of the counting device, a signal is transmitted to a counter through a signal transmission line, and the number of the packaging formed products is recorded; and the sum can be read through the counter fixed to an installing support, and the installing support is fixed to the rack. According to the design of the automatic counting packaging machine for medicine packaging, the number of the products is counted, waste of human resources is reduced, and the work efficiency of the medicine powder packaging machine is improved.

The invention provides a thrombus thrombolysis device, and belongs to the technical field of medical instruments. The thrombus thrombolysis device comprises a thrombolysis catheter, the interior of the thrombolysis catheter is of a hollow structure, the far end of the thrombolysis catheter is provided with a thrombolysis section, and the far end of the thrombolysis section is provided with a first developing ring; a plurality of dosing towers protruding outwards in the radial direction are arranged on the side wall of the thrombolysis section, channels communicated with the interior of the thrombolysis catheter are arranged in the dosing towers, and dosing outlets are formed in the top ends of the dosing towers; according to the thrombus thrombolysis device, due to the fact that the drug delivery towers protruding outwards in the radial direction are arranged on the thrombolysis section of the thrombolysis catheter, when the thrombolysis section of the thrombolysis catheter is inserted into a thrombus area, the drug delivery towers can be inserted into a thrombus, and therefore thrombolysis drugs can reach the inside of the thrombus through the drug delivery towers, the thrombolysis efficiency of the thrombus is improved. The thrombolysis time can be shortened, and the thrombolysis effect on old thrombus can be enhanced.

A drug injection device (1) comprising a dose expelling mechanism for expelling drug from a reservoir through a reservoir outlet, the dose expelling mechanism comprising: a first component (40), a second component (10, 10′, 15′, 10″, 15″), and a torsion spring element (20) for inducing relative rotation between the first component (40) and the second component (10, 10′, 15′, 10″, 15″) to execute a dose expelling operation, the torsion spring element (20) extending along a longitudinal axis and comprising: a first spring end portion (22) being rotationally restrained with respect to the first component (40), and a second spring end portion (23) exhibiting an end portion inner diameter in a relaxed state of the torsion spring element (20), wherein the second spring end portion (23) is fitted over a spring receiving portion (11) of the second component (10, 10′, 15′, 10″, 15″), the spring receiving portion (11) having a transversal dimension which is larger than the end portion inner diameter, and the fitting of the second spring end portion (23) over the spring receiving portion (11) being configured to provide a sticking friction engagement between the two when the torsion spring element (20) is strained to exert a maximum in-use torque.

The invention relates to the technical field of medical apparatuses and instruments, in particular to a dosing device for cleaning in the anorectal department and a manufacturing method thereof. The dosing device for cleaning in the anorectal department comprises a dosing rod, a blind hole is formed in one end of the dosing rod in the length direction of the dosing rod, a plurality of dosing holes are formed in the peripheral side wall of the other end of the dosing rod in the circumferential direction, and all the dosing holes communicate with the blind hole; a rubber sleeve sleeves the dosing rod, a plurality of long-strip seams are formed in the rubber sleeve, the long-strip seams directly face the corresponding dosing holes, the long-strip seams are expanded under extrusion of liquid medicine output by the dosing holes, the dosing holes in the side wall of the dosing rod and anus plica of a patient can be separated under the condition that normal drug delivery and cleaning can be guaranteed, and therefore, damage to the anus plica of the patient when the dosing device is inserted into the anus of the patient is avoided, and treatment experience is improved while new anus damage is prevented. The manufacturing method of the dosing device can be used for manufacturing the dosing device for cleaning in the anorectal department.