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12 results about "Phospholipid" patented technology

Phospholipids are a class of lipids that are a major component of all cell membranes. They can form lipid bilayers because of their amphiphilic characteristic. The structure of the phospholipid molecule generally consists of two hydrophobic fatty acid "tails" and a hydrophilic "head" consisting of a phosphate group. The two components are usually joined together by a glycerol molecule. The phosphate groups can be modified with simple organic molecules such as choline, ethanolamine or serine.

Cefmetazole sodium proliposome preparation

ActiveCN101623264AThe encapsulation efficiency has not decreasedImprove stabilityOrganic active ingredientsAntibacterial agentsCholesterolPhospholipid
The invention provides a cefmetazole sodium proliposome preparation which comprises the following components by weight part: 1 part of cefmetazole sodium, 3-15 parts of liposome carrier and 2-10 parts of proppant, wherein the liposome carrier comprises polyene phosphatidyl choline, cholesterol and oleinic acid according to a weight ratio of (4-20):(1-5):1. The cefmetazole sodium proliposome preparation has good preparation stability and cannot crack because of dewatering, fusion, ice crystal generation, and the like in a freeze-drying process; and after hydrated re-dissolution, the cefmetazole sodium proliposome preparation still can maintain good entrapment rate.
Owner:HAINAN LINGKANG PHARMA CO LTD

Preparation method of phosphatidylglycerol monosodium salt containing two different side chains

PendingCN111057100AHigh purityHigh yieldPhosphatide foodstuff compositionsPhosphorus organic compoundsSide chainPhospholipid
The invention belongs to the technical field of compound preparation. The invention relates to a preparation method of phosphatidylglycerol monosodium salt, in particular to a preparation method of phosphatidylglycerol monosodium salt containing two different side chains. The preparation method comprises the following steps: taking D-mannitol as an initial raw material, heating D-mannitol in acetone to generate 1,1,5,6-isopropylidene-D-mannitol; carrying out sodium periodate oxidation and sodium borohydride reduction to obtain iso-propylidene glycerol; carrying out condensation reaction with fatty acid containing an R1 element, then removing acetal protective groups in the presence of acid; selectively protecting primary hydroxyl by using a silane protective agent, reacting secondary hydroxyl with another fatty acid containing a R2 element, removing silane protection, reacting the de-protected product with phosphorus oxychloride and iso-propylidene glycerol, removing acetal protectivegroups by using an acid, and finally carrying out a sodium salt treatment to obtain a final product. The synthesis of phosphatidyl monosodium salt containing two different side chains can be realized,and the production process is simple, environment-friendly and easy to operate.
Owner:HEFEI BOSIKC PHARMTECH CO LTD

Mold release agent for wood-plastic composite material

InactiveCN108972977AExtended service lifeFixedPhospholipidNitrogen gas
The invention discloses a preparation method of a mold release agent for a wood-plastic composite material, and belongs to the technical field of polymer materials. The mold release agent is preparedfrom the following materials in parts by weight: 8 to 10 parts of a plasticizer, 3 to 5 parts of phospholipid, 5 to 8 parts of an emulsifier, 8 to 10 parts of a dispersant aqueous solution, 8 to 10 parts of pretreated dicyclohexyl peroxydicarbonate, and 200 to 300 parts of water; the preparation method comprises the steps of adding the water into a polymerization kettle, heating, then adding the plasticizer, the phospholipid, the emulsifier, the dispersant aqueous solution, pretreated dicyclohexyl peroxydicarboxylate, stirring and mixing, introducing nitrogen containing vinyl chloride, keepingtemperature and pressure and stirring for reaction, then, adding a terminator with the mass being 0.03 to 0.05 times of that of the plasticizer, releasing pressure, and cooling and discharging to obtain the release agent for the wood-plastic composite material. The release agent for the wood-plastic composite material prepared by the preparation method provided by the invention has the characteristic of excellent mold release effect, and has broad prospects in the development of the polymer material technology industry.
Owner:何治伟
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