The invention relates to a method of establishing a crania-cerebral explosion
impact injury
animal model in the
medical research field. The method of establishing the crania-cerebral explosion
impact injury
animal model is characterized in that a big rat (7) is fixed on a shield plate (2) with a window hole (3), a back side of a head of the big rat (7) is aligned at the shield plate window hole (3), only the back side of the head of the rat (7) can be suffered hurts of shock
waves; the shield plate (2) is fixed, a pressure
detector (9) and an explosion source (8) are arranged on the same horizontal level of the shield plate window hole (3), a distance between the explosion source (8) and the shield plate window hole (3) is equal with a distance between the explosion source (8) and the pressure
detector (9); injuries are caused by
initiation of an explosion,
shock wave pressure data and
head injury conditions of the big rat are recorded, the crania-cerebral explosion
impact injury
animal model is established. Defects that a vulnerated mechanism and a traumatic condition are difficult to be analyzed by a
single factor in the existing technology are overcome. The method of establishing the crania-cerebral explosion impact injury animal model has the advantages that a structure of an experimental device is simple, bearing
shock wave size conditions of the animal head can be reflected by data of the
detector, and the injuries are caused by the head exposed purely.