The invention relates to the field of particle imaging and relates to a particle imaging method and a particle imaging device. The particle imaging device mainly comprises a cluster source, a vacuum chamber, a flow divider, an ionic lens I, a gate valve I, an ionic lens II, a gate valve II, a mass filter, a microchannel disk I, a shielding cover, a voltage reference tube, a velocity imaging electrode set, a microchannel disk II, a detector, a laser I and a vacuum pump set, wherein the cluster source comprises a liquid storage tank, a flow controller, a sample feeding tube, an air pipe, an airstorage tank, a protection cavity, a condensing cavity, a heater, a sample cavity, a nozzle and a laser II. An air accumulation and laser evaporation combined method is utilized to generate doped macromolecule clusters, so that the sizes of the clusters are evener; furthermore, the doped measurement in the clusters is accurate and controllable, and the generated clusters can be quickly cooled; a method of switching voltage on an electrode is utilized to effectively gather the clusters, so that the light reaction strength is improved, and the light reaction efficiency is improved.