12 results about "Glucan" patented technology

The invention discloses a mussel-imitated underwater high-viscosity hydrogel preparation method, which comprises: (1) dissolving chitosan in acetic acid to prepare a chitosan acetic acid solution; (2)adding 3,4-dihydroxyphenylacetic acid, EDC and NHS into the solution prepared in the step (1), adjusting the pH value, and carrying out a reaction for a certain time; (3) dialyzing the solution obtained in the step (2) in water with the pH value of 5, taking the trapped fluid, and carrying out freeze-drying; (4) preparing the sample obtained in the step (3) into a solution; (5) dissolving glucanin water, adding an oxidant, reacting for a certain time in a dark place, and then adding ethylene glycol to terminate the reaction; (6) dialyzing the solution obtained in the step (5) in water, taking the trapped fluid, and carrying out freeze-drying; (7) preparing the sample obtained in the step (6) into a solution; and (8) mixing the solutions obtained in the step (4) and the step (7) to obtainthe hydrogel. According to the preparation method provided by the invention, the prepared hydrogel can be used as an underwater adhesive.

The invention discloses a temperature-sensitive wall material. The temperature-sensitive wall material comprises a temperature-sensitive material modified polymer wall material, wherein the temperature-sensitive material is polyvinylpyrrolidone, glycerophosphate, stearic acid, galactose-removed xyloglucan or gelatin-chitosan, poly(N-isopropylacrylamide) and hydroxybutyl chitosan. The temperature-sensitive wall material releases drugs at different temperatures, the drug release time is flexibly controlled, the phytotoxicity is reduced, and the drug action time is prolonged. The temperature-sensitive wall material can be applied to whole-course pesticide application protection of the growth cycle of crops, the chemical application frequency is reduced, and the crop management efficiency is improved. The invention also provides a corresponding microcapsule and a preparation method.

The invention relates to the field of medicinal materials and discloses a synthetic method and application of a glucan/indometacin graft. According to the synthetic method and the application, the problem that certain drugs have serious toxic and side effects is solved. 4-dimethylaminopyridine (DMAP) is taken as a catalyst, carbodiimide (EDC) is taken as a dehydrating agent, glucan and indometacin are respectively taken as a hydrophilic skeleton and a hydrophobic chain segment, and hydroxide radicals in a chemical structure of glucan (Dex) generate esterification reaction with carboxyl in a chemical structure of indometacin (Indo) to generate an amphipathic compound, namely the glucan/indometacin graft. A drug delivery system which is prepared from the glucan/indometacin graft and loaded with an indissolvable drug polymer nanoparticle solution has relatively high drug loading capacity and encapsulation efficiency, presents hypotoxicity and can be used as a drug carrier.

The invention relates to a method for determining content of crosslinked glucan filled in sodium hyaluronate gel. The method comprises the following steps: 1) using a pyrolysis gas chromatography-massspectrometry method for pyrolysis analysis of a plurality of groups of pure crosslinked glucan products with different masses and obtaining the linear relationship between the peak area and the massof a characteristic cracking peak according to a pyrolysis chromatogram; wherein the characteristic cracking peak is a characteristic cracking peak of glycerol; 2) performing the pyrolysis analysis ona sample to be tested, obtaining the peak area of the characteristic cracking peak of the sample to be tested according to the appearance time of the characteristic cracking peak, and obtaining the mass or content of the crosslinked glucan filled in the sample to be tested. The method is simple and quick to operate, and is accurate and reliable in results.

The invention discloses an application of beta-glucan and succinyl glycan in prevention and control of soil-borne fungal diseases. A method comprises the following steps: adding a mixture of beta-glucan and succinyl glycan into soil; so that the increase of the quantity of streptomyces in soil and the increase of the activity of hydrolase such as beta-glucanase, chitinase and cellulase in the soilare induced, and effectively prevent and control on various soil-borne pathogenic fungus diseases through the combined action of streptomyces and various hydrolases can be realized. The method has the advantages of wide sources of required raw materials, simple operation, better effect than single use of one polysaccharide, and good environmental compatibility.

The invention discloses a nanocellulose-pectin microcapsule and a preparation method and application thereof. The preparation method includes the following steps that (1) orange nanocellulose is subjected to oxidization with an oxidant, and then is subjected to cationic modified reaction with a modifier to obtain cationic nanocellulose; (2) a dextran solution containing pectin is prepared and recorded as a solution A; and a polyethylene glycol solution containing the cationic nanocellulose is prepared and recorded as a solution B; and (3) following steps (1) or (2) is adopted to prepare and obtain the nanocellulose-pectin microcapsule; (1) a millimeter level microcapsule is prepared through a drop injection method, drops of the solution A are dropped into the solution B, and a millimeter level nanocellulose-pectin microcapsule is obtained after reaction; and (2) a micron level microcapsule is prepared through a microcapsule granulator, the solution A is dropped and sprayed into the solution B, and then reacted in the microcapsule granulator to obtain a micron level nanocellulose-pectin microcapsule. The nanocellulose-pectin microcapsule has good biocompatibility and high biosafety.

The invention provides whole blood simulation liquid for in-vitro test of a hollow fiber blood purification device. The whole blood simulation liquid comprises particulate matter and simulation liquid in a volume ratio of (1: 1)-(1: 9), the particulate matter is selected from silicon dioxide particles or polystyrene microspheres; the simulation liquid is composed of soluble macromolecules and water; the soluble macromolecules are selected from at least two of glucan, hydroxyethyl starch, albumin, lysozyme and myoglobin; the proportion of water in the simulation liquid does not exceed 95 wt%. The in-vitro whole blood simulation liquid is adopted to simulate blood, so that the uniformity of a test system can be ensured, and the instability of a test result caused by the difference between different batches of bovine blood is avoided.

The invention discloses a method for synthesizing sugar-undisturbed alpha-glucan with different tightness degrees in vitro, and belongs to the field of food, medicine and starch sugar production. According to the invention, sugar-undisturbed alpha-glucan (GnG) with a certain molecular weight can be synthesized by taking sucrose as a substrate through an SP-GP-BE three-enzyme method; the looseness degree of an outer side chain of the GnG can be controlled by adjusting the ratio of GP to BE, so that different GnG samples with the particle size within the range of 44-54 nm are obtained; and the looseness degree of GnG molecules is improved along with the increase of the ratio of GP/BE. On the basis of controlling GP/BE, the concentration of maltotriose in a reaction system is adjusted; the molecular weight of GnG is reduced along with the increase of the concentration of maltotriose; and meanwhile, the molecular looseness degree of the GnG is increased. According to the method disclosed by the invention, the looseness degree of the GnG molecules can be adjusted by adjusting the GP/BE ratio or adjusting the concentration of maltotriose.

The present invention addresses the problem of providing an inhibitor for blood glucose level increase, which can be daily, easily, safely and continuously taken after the intake of a monosaccharide by those who are worrying about blood glucose level including healthy persons, and an oral composition comprising the same. To solve this problem, provided are: an inhibitor for blood glucose level increase that comprises a branched [alpha]-glucan mixture characterized by (A) comprising glucose as a constituent sugar, (B) having a branched structure of a glucose polymerization degree of 1 or higherthat is bonded, via a bond other than an [alpha]-1,4 bond, to a non-reducing terminal glucose residue positioned at one end of a linear glucan bonded via an [alpha]-1,4 bond and having a glucose polymerization degree of 3 or higher, and (C) forming isomaltose when digested by isomaltodextranase; and an oral composition that comprises the inhibitor for blood glucose level increase together with amonosaccharide.