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10 results about "Propanoic acid" patented technology

Propionic acid (/proʊpiˈɒnɪk/, from the Greek words protos, meaning "first", and pion, meaning "fat"; also known as propanoic acid) is a naturally occurring carboxylic acid with chemical formula CH₃CH₂CO₂H. It is a liquid with a pungent and unpleasant smell somewhat resembling body odor. The anion CH₃CH₂CO₂⁻ as well as the salts and esters of propionic acid are known as propionates or propanoates.

Preparation method of sodium ibandronate

InactiveCN102898466AEasy to operateMeet the quality requirements of raw materialsGroup 5/15 element organic compoundsSkeletal disorderPhosphorous acidChlorobenzene
The invention relates to the technical field of pharmaceutical chemistry, particularly relates to a method of pharmaceutical synthesis, and specifically relates to a preparation method of sodium ibandronate. To overcome the disadvantages of high content of chlorides and phosphites in sodium ibandronate prepared by a conventional preparation method of sodium ibandronate, the preparation method of sodium ibandronate with extremely low content of chlorides and phosphites is provided. In the preparation method, 3-(N-methylpentylamino) propionic acid hydrochloride, phosphorus trichloride and phosphorous acid are employed as raw materials and reacted in a chlorobenzene solvent, so as to obtain sodium ibandronate with extremely low content of the chlorides and the phosphites. The obtained sodium ibandronate can not only meet impurity control standards of the chlorides and the phosphites in a sodium ibandronate crude drug, but also prevent low yield, long period and huge harm to human body and environment which are brought by a lot of refining steps.
Owner:JIANGSU AOSAIKANG PHARMA CO LTD

Special feed additive for animal intestines

The invention discloses a special feed additive for animal intestines. The feed additive is prepared from the following raw materials in percentage by weight: 15-20% of an enzyme preparation, 30-60% of a fermentation material, 10%-20% of bentonite, 0.5%-1% of multi-vitamin, 1%-5% of multi-mineral, 0.5%-2% of a mildew preventive, 0.5%-2% of an antioxidant, 2%-20% of zeolite powder, wherein the enzyme preparation is a plurality of compound enzymes such as protease, cellulase, glucolase and xylanase, the fermentation material is a substrate for fermentation of a microecological preparation, the multi-vitamin comprises vitamin A, vitamin D3, vitamin E, vitamin B1 and vitamin B2, the multi-mineral comprise a plurality of trace elements: copper glycinate, zinc glycinate and iron glycinate, the main components of the mildew preventive are propionic acid, calcium propionate and benzoic acid, and the main components of the antioxidant are ethoxyquinoline and butylated hydroxytoluene. The special feed additive for animal intestines is high in overall utilization rate, improves the egg laying efficiency of old laying hens, and can be widely popularized and used.
Owner:KUNMING YUNNAN NONGDA BIOLOGICAL TECH CO LTD

Intravascular stent comprising biodegradable macromolecular coating

InactiveCN107812245AGood biocompatibilityPromote degradationSurgeryFermentationWater bathsPropanoic acid
The invention discloses a vascular stent containing a biodegradable polymer coating, which belongs to the medical field. The preparation method is as follows: step 1, inserting the bacterial strain into a medium for cultivation, and culturing at 25-30°C for 40 hours; Step 2. Inoculate the above-mentioned culture solution into the fermentation medium according to the inoculation amount of 5%, and cultivate it at 25-30°C for 48 hours; Step 3. Centrifuge the above-mentioned fermentation solution for 20 minutes, collect the cells, and heat them in a water bath. Take the supernatant, drain the water, and prepare polylysine; step 4: dissolve 2-amino-3-p-hydroxyphenylpropionic acid monomer and peroxide initiator in an organic solvent to prepare a solution; Secondly, it is mixed with the prepared polylysine powder, and the mixture is grafted and modified by melt grafting reaction equipment to obtain polylysine grafted 2-amino-3-p-hydroxyphenylpropionic acid biodegradable polymer.
Owner:CHENGDU CEDISEN BIOTECHNOLOGY CO LTD

Composition for resisting propionibacterium acnes and regulating skin micro-ecology and application thereof

PendingCN111053887APromote Microecological BalanceImpaired film-forming growthBiocideOrganic active ingredientsBiotechnologyAcne preparations
The invention belongs to the technical field of medical biology and discloses a composition for resisting propionibacterium acnes and regulating skin micro-ecology. The composition comprises the following components (by weight): 0.5-3 parts of nisin, 0.1-2 parts of polylysine, 0.1-2 parts of cordycepin, 0.1-1 part of lysozyme, 10-50 parts of water and 0.5-4 parts of a pH regulator. The compositionhas a remarkable antagonistic effect on the growth of propionibacterium acnes and staphylococcus aureus, and can weaken the film-forming growth of propionibacterium acnes, so that the skin invasiveness of propionibacterium acnes is weakened, the occurrence and development of acnes are intervened, and then the effect of preventing and treating acnes is achieved. According to the composition, the microbial flora on the surface of the skin is regulated to help recover the micro-ecological balance of the skin; and most of the main components of the composition can be degraded into amino acids, sothat a part of nutrient matrix can be provided for skin repair. The composition can be added into a skin micro-ecology regulating preparation, an anti-acne preparation or an acne removing preparation.
Owner:HUZHOU ZHONGKE JINYI MEDICAL TECH CO LTD
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