15 results about "Hormone" patented technology

The invention discloses a microbial improvement method for soil of an abandoned land of a mine. The method comprises the following steps of step 1, soil stabilization and plant surface planting through bacillus subtillis, wherein antibiotics are generated, hormones stimulating the plant growth are secreted, and host microorganisms are trapped and killed; step 2, nitrogen fixation, wherein gaseousnitrogen in the atmosphere is fixed through nodule bacteria, brown nitrogen-fixing bacteria and frankiaceae for providing nitrogen nutrients for plants; step 3, phosphorus and potassium adding, wherein potassium, silicon and phosphorus in soil minerals are decomposed through bacillus mucilaginosus; step 4, phosphorus and potassium dissolving. The microbial improvement method for the soil of the abandoned land of the mine has the advantages that through multi-proportion addition of a microbial agent, the introduction of harmful microbes is controlled and cut off, beneficial microbes are cultivated, the soil is improved continuously through the action of the beneficial microbes, heavy metals are controlled, chelated and conditioned through the decomposition characteristics of the cultivatedmicrobes, the PH value of the soil is neutralized, soil ripening is accelerated to improve the soil, the self-purification action is strengthened, and natural circulation is accelerated to improve thehealthy growth of hyperaccumulators.

The invention provides a composition for skin allergy and impaired skin barrier and a preparation method thereof. The composition comprises the following components by weight percent: 8-12% of purslane extract, 3-7% of gentina root extract, 3-7% of sophora root extract, 3-7% of snowparsley extract, 3-7% of asiaticoside, 1-5% of densefruit pittany root-bark extract, 0.5-1.5% of artesunate, 1-3% oflicorice extract, 0.5-1.5% of ceramide, 0.3-0.9% of cholesterol, 0.2-0.6% of fatty acid, 15-27% of butanediol and 35-47% of deionized water. The composition disclosed by the invention mainly adopts traditional Chinese medicine components, is safe and effective, and has the effects of calming and relieving itching, relieving heat and diminishing inflammation and reducing swelling and removing dampness for facial allergy, hormone dependent dermatitis, acne rosacea and the like; and meanwhile, due to long-term use, the composition can achieve the effects of gradually improving erythema and desquamation, promoting keratinized cell differentiation maturation and repairing skin barrier to stabilize.

The invention discloses an action target spot of glucocorticoid and application thereof, particularly discloses an action target spot of FoxO3a which is glucocorticoid, and provides a method for screening a glucocorticoid compound, a method for screening a compound for inhibiting FoxO3a phosphorylation, a method for improving the sensitivity of a cell on glucocorticoid, a method for detecting thesensitivity of the cell on the glucocorticoid and a kit.

The invention relates to a microneedle for treating leucoderma as well as a preparation method and application thereof, and relates to the field of medical biological materials. The microneedle comprises hydrogel, a water-soluble substrate material and an active pharmaceutical ingredient, the active pharmaceutical ingredient is selected from at least one of the following raw materials: melanotropin, tofacitinib, tacrolimus, pimerolimus or ruxolitinib. According to the microneedle, hydrogel with high mechanical strength is adopted, the microneedle can pierce the cuticle, the hydrogel is insoluble in water, the prepared microneedle does not need a large amount of organic solvent, after the microneedle pierces the cuticle, the medicine for treating leucoderma is directly delivered to the epidermal layer and the corium layer through the diffusion effect, and the medicine application effect is enhanced; meanwhile, the substrate of the microneedle is made of a water-soluble substrate material, after the skin is punctured by the microneedle, water is absorbed, the tip of the microneedle and the substrate of the microneedle are automatically separated, and the tip which is insoluble in water is remained in the skin, so that active pharmaceutical ingredients attached to the microneedle are released in a long-acting manner, and the administration frequency is reduced.

The invention relates to activators of FXR useful in the treatment of autoimmune disorders, liver disease, intestinal disease, kidney disease, cancer, and other diseases in which FXR plays a role, having the Formula (I): wherein L₁, A, X₁, X₂, Y₁, Y₂, Y₃, Y₄, R¹, R², and R³ are described herein.

Provided is a means with which it is possible to efficiently prevent or improve symptoms caused by an imbalance of sex hormones with as little pain as possible, and which can safely be taken daily. A compound selected from the group consisting of a lophenol compound and a cyclolanostane compound is used as an active ingredient of an agent for preventing or improving symptoms caused by an imbalance of sex hormones.

The invention relates to a tissue culture method of syringa microphylla diels and a method for rapidly obtaining large syringa microphylla diels seedlings. The tissue culture method comprises the following steps of (1) explant selection and disinfection: cutting the top end part of an annual tender branch, cutting the top end part into a stem segment with a terminal bud or 1-2 axillary buds as anexplant, and carrying out disinfection treatment; (2) starting culture: putting the explant into a starting culture medium, and enabling the terminal bud or the axillary bud to be just in contact withthe culture medium until the terminal bud or the axillary bud germinates, wherein the starting culture medium takes an MS culture medium as a basic culture medium, 30g/L of saccharose, 6g/L of agar,1mg/L of hormone 6-BA and 0.2 mg/L of hormone NAA are added at the same time, and the pH is adjusted to 5.8-6.2; (3) carrying out subculture; (4) performing rooting culture; and (5) performing transplanting to obtain tissue culture seedlings. According to the method, the survival rate of the syringa microphylla diels explants in the starting culture process is high, calluses are not prone to appearing, and the induction rate of axillary buds or terminal buds is high.