42results about "Bulk chemical production" patented technology

The invention relates to a method for preparing an organic starch ester. The method comprises mixing a starch material with an ionic liquid solvent to dissolve the starch, and then treating the dissolved starch with an organic esterifying agent to form an organic starch ester, and subsequently separating the organic starch ester from the solution. Microwave irradiation and/or pressure can be applied to assist in dissolution and esterification.

The invention relates to a method for directly preparing propylene from crude methanol, wherein, in an integrated unit for preparing the methanol and preparing the propylene from the methanol, the crude methanol directly enters a multistage adiabatic fixed bed reactor loaded with an acid molecular sieve catalyst without rectification and purification to prepare low carbon olefin with the propyleneas a main component. In the method, steam and circulating hydrocarbon as diluent, and a mixture of the crude methanol and water is used for interstage cold shock to control reaction temperature of the reactor in each stage. The method helps obtain high propylene yield, and obviously reduce investment and energy consumption of the integrated unit for preparing the methanol and preparing the propylene from the methanol.

The invention provides a method for separating aromatic hydrocarbon from alkane by ionic liquid and membrane process coupling technology. The method includes that a hollow fiber membrane component is used as an extraction and separation device, ionic liquid is filled in pores of a hollow fiber membrane to form extract, aromatic hydrocarbon and alkane mixed liquor and a back-extraction phase respectively flow in a tube pass and a shell pass of the hollow fiber membrane in parallel or reversely, aromatic hydrocarbon is preferentially transferred to the back-extraction phase via the extract owing to the difference between the solubility of the aromatic hydrocarbon and the solubility of alkane in the ionic liquid, and the purpose of separating the aromatic hydrocarbon from the alkane is achieved. The method has the advantages of good selectivity, high mass transfer efficiency, low dosage of extracting solvent, simplicity in technological process, high stability and the like.

The invention discloses an activated carbon-supported ruthenium-based ammonia synthetic catalyst and a preparation method thereof. The preparation method comprises the steps of with potassium ruthenate K2RuO4 H2O as a metallic ruthenium precursor, liquid ammonia and acetic acid as a stabilizer of ruthenium impregnation liquid, alkaline metal and alkaline-earth salts or bases as aids, and activatedcarbon as a supporter, performing impregnating to obtain the activated carbon-supported ruthenium-based ammonia synthetic catalyst. The activated carbon-supported ruthenium-based ammonia synthetic catalyst prepared herein is free of chlorine ions; active ingredients and the aids are distributed evenly on the catalyst; the prepared catalyst has stable performance, high activity, and good safety ofuse and is suitable for industrial production and application.

The invention relates to the field of preparation of biologic oil, and provides a furfural catalytic hydrogenation method under supercritical carbon dioxide and a method for preparing catalysts. The furfural catalytic hydrogenation method under supercritical carbon dioxide comprises the steps that furfural and palladium and carbon catalysts are added to a reaction still, then the reaction still is sealed, hydrogen is introduced into the reaction still to remove the air in the reaction still, liquefied carbon dioxide is injected into the sealed reaction still through a plunger metering pump, the pressure of the carbon dioxide is made to be above the critical pressure when the carbon dioxide is in an overcritical state, furfural catalytic hydrogenation and upgrading are carried out under the overcritical condition of the carbon dioxide, and a needed liquid product is prepared. The method for preparing the palladium and carbon catalysts comprises the steps of pre-processing of a carrier and preparation of the palladium and carbon catalysts (Pd/C catalysts). In the reaction process, the catalysts have no carbon accumulation phenomenon, can be recycled, largely reduce generation of by-products, and improve the selectivity of the products.

A catalyst for production of propylene through catalytic dehydrogenation of propane adopts alumina-chrome oxide as a mixed carrier, metallic Pt as an active component and metallic Sn, La and Ca as assistants, the chemical formula of the catalyst is Pt-Sn-Ca/Cr2O3.Al2O3 and Pt-Sn-La-Ca/Cr2O3.Al2O3, and a mass ratio of Cr2O3 to Al2O3 in the mixed carrier is 2:1. A preparation method of the catalyst has the advantages of simple process and easy operation; a performance test result of the catalyst shows that the catalyst has high propane conversion rate, high activity, long service life and high propylene selectivity; and the initial conversion rate is about 48%, and the catalyst still has a high conversion rate of about 40% and high propylene selectivity of above 91% 4h later, so the catalyst has a great economic effect, and can be industrially popularized.

Processes for preparing a calcium salt of a statin from an ester derivative or protected ester derivative of the statin by using calcium hydroxide are provided. The ester or protected ester derivative is contacted with calcium hydroxide to obtain the calcium salt. Preferred statins are rosuvastatin, pitavastatin and atorvastatin, simvastatin and lovastatin. In processes beginning with a protected statin ester derivative, the protecting group is hydrolyzed during salt formation by contact with calcium hydroxide, or is contacted with an acid catalyst followed by contact with calcium hydroxide.

The invention discloses a super heat insulation coating loaded with nano titanium dioxide. The super heat insulation coating is prepared from the following raw materials in parts by weight: 38-42 parts of ethyl orthosilicate, an appropriate amount of ethanol and deionized water, 0.1-0.2 part of maleic anhydride, 0.7-0.9 part of hexamethyldisilazane, 0.4-0.5 part of 3-aminopropyl triethoxysilane, 0.4-0.5 part of nano titanium oxide, 70-75 parts of E-12 epoxy resin, 9-12 parts of ethylene glycol diglycid ether and 7-7.5 parts of triethanolamine. The coating disclosed by the invention uses silicon dioxide aerogel and has a super heat insulation property; by loading nano titanium dioxide to the aerogel, the ageing process of the aerogel is retarded, and the service life of the aerogel is prolonged; and by using hexamethyldisilazane to perform modification, the hydrophilic property of the aerogel is improved, and the phenomenon that the aerogel is broken up and degraded by absorbing water is reduced.

The invention discloses an oxidation-resistant polymer film with memory function. The oxidation-resistant polymer film with memory function is prepared from carboxylated graphene oxide, nano silicon dioxide, modified kudzu root starch, nano silver, curcumin, proanthocyanidin, vinyl triguaiacyl trimethoxy silane, epoxy soybean oil, nitrile-butadiene rubber powder, tetramethylsilane, dodecylbenzene sulfonic acid, paraffin oil, meerschaum wool, metallocene polyethylene and a polypropylene random copolymer. The polymer film has the advantages of simple components, low cost, no toxicity, no corrosiveness, no impurity, bright surface, impact resistance and tear resistance, is non-combustible, has favorable service performance, and is green and environment-friendly. The polymer film has low ash content, and can enhance the electric properties and high cleanliness of capacitors. The polymer film has excellent heat resistance, is non-combustible, and has high electrochemical activity. The polymer film has high oxidation resistance and stable performance, and thus, can obviously enhance the user stability and service life of the capacitors. The polymer film has the characteristics of high mechanical properties, acid/alkali resistance, corrosion resistance and high recoverability.

The invention discloses a method for preparing hydrogen by utilizing waste biomass, and the method comprises the following steps of: firstly, processing the waste biomass into semi-finished product fluid slurry; then, carrying out water vapor gasification treatment on the semi-finished product fluid slurry, thus obtaining crude oil; carrying out supercritical water gasification treatment on the crude oil, thus obtaining crude bio-gas; and finally, carrying out low-temperature transformation treatment on the crude bio-gas, thus obtaining transformed gas. The hydrogen is prepared by two-step gasification and low-temperature transformation, so that the biomass gasification efficiency is high, tar carbon deposit blockage can be avoided, continuous feeding is realized, and the prepared hydrogen is high in purity; furthermore, in the low-temperature transformation treatment, precious metals and rare-earth elements are added on the basis of a copper-zinc-aluminum catalyst, so that the reaction temperature is remarkably reduced, the activity and stability of the catalyst are improved, and the conversion rate of CO is high during the low-temperature transformation treatment.

The invention discloses a combined method for treating kitchen waste and waste plastics to prepare hydrogen-rich fuel gas. The method comprises the following steps: crushing the collected kitchen waste and waste plastics, and conveying the crushed material to a supercritical water gasification reaction kettle, wherein the reaction kettle is filled with nitrogen gas; heating and pressurizing the reaction kettle by using an electric heater to 420 DEG C and 23-25 MPa, respectively; performing a reaction continuously for 40-60 min, and stirring the material at the rotation speed of 100-150 rpm byusing a magnetic stirrer; after the reaction is completed, cooling the reaction kettle to room temperature by using cooling water; and collecting the high-quality hydrogen-rich fuel gas by using an air pump, drying the gas, and performing storage. The method can realize the efficient treatment of the kitchen waste and the waste plastics; the synthesis gas produced by the kitchen waste and the waste plastics combined with supercritical water gasification has a high hydrogen concentration and high quality; and the secondary pollution to the environment in the treatment process is greatly reduced.

The invention relates to the field of polyethylene catalysis, in particular to a metallocene catalyst component for preparing polyethylene wax and application thereof. When the metallocene catalyst component is applied to ethylene polymerization, the metallocene catalyst component has the characteristics that the polymerization activity is high, no hydrogen is released, and the hydrogen regulationsensitivity is high. The metallocene catalyst component is very suitable for production of high-crystallinity polymerized wax. When the metallocene catalyst component is used for ethylene polymerization, no hydrogen release effect exists, the concentration of hydrogen in a reaction system is kept stable on the premise that the input and output quantities are balanced, the molecular weight of polyethylene wax generated by polymerization is also kept stable, and the performance of the produced polyethylene wax product is also kept stable.

The invention discloses a Ni3P/SiO2 catalyst as well as a preparation method and application thereof. The Ni3P/SiO2 catalyst is composed of a SiO2 carrier and Ni3P loaded on the SiO2 carrier, the mass percent of Ni3P in the catalyst is 10-45%, the balance is the SiO2 carrier, the particle size of Ni3P in the catalyst is 6-15 nanometers, and the specific surface area of the catalyst is 50-250 m<2>/g. Experiments show that the Ni3P/SiO2 catalyst provided by the invention is high in activity, high in selectivity and good in stability, especially has the advantages that the selectivity of methyl glycolate can still reach 85% or above under deep conversion of dimethyl oxalate (greater than 99.9%), a high-selectivity temperature window is wide and the like, and can be used as a catalyst for a reaction of preparing methyl glycolate through hydrogenation of dimethyl oxalate; and in addition, the preparation method disclosed by the invention is simple, mild in condition and easy to realize large-scale production.

The invention discloses a recycling method of an epoxy resin composite material, obtained glass fibers and application of the glass fibers, and relates to the field of organic solid material recycling. The preparation method specifically comprises the following steps: S1, mixing an epoxy resin composite material and a composite solvent, placing the mixture in a pressure container, and controlling the reaction temperature to be 120-150 DEG C and the reaction time to be 3-7 hours to prepare a solid-liquid mixture; and S2, filtering the solid-liquid mixture to obtain decomposition filtrate and a solid-phase product, wherein the solid-phase product is glass fibers, and the glass fibers are applied to the fields of waterproof base materials, energy-saving auxiliary reinforcing materials, reinforced cementing materials, building decoration materials and the like. The composite solvent is used for degrading the epoxy resin composite material, the experimental process is simple, the reaction condition is mild, the performance of the obtained product is excellent, and the composite solvent is environmentally friendly and has economic benefits.

The invention discloses a polypeptide for inhibiting cell proliferation and inducing apoptosis and a preparation method and use thereof. The polypeptide disclosed by the invention comprises a polypeptide sequence 'SPHSG', namely YGRKKRRQRRR-GYLSKVRGISEVL, or another polypeptide sequence 'MRSP', which is similar to the polypeptide sequence in homology and function, namely YGRKKRRQRRR-DVKGYLSKVRGISEVL. An experimental basis is provided for application of the polypeptide in a coated balloon or a coated bracket. Compared with the traditional coated drug, the polypeptide does not have toxic or side effects and immunogenicity of chemical drugs as a small segment of Mfn2. The practicability is also superior to rapamycin. Therefore, the polypeptide has a wide application prospect and great clinical application value.

The invention discloses a synthesizing method of a single-configuration rabeprazole metabolite.According to the method, rabeprazole thioether serves as a starting material, and the rabeprazole metabolite is synthesized through a five-step reaction.The optimal preparation steps and reaction conditions are screened out through a large number of experiments, the whole technological design is reasonable, and the operability is high.According to the obtained single-configuration rabeprazole metabolite, the chemical purity can reach 99% or above, and the chiral purity is larger than 99.5%.The obtained single-configuration rabeprazole metabolite provides a standard substance for metabolic mechanism research of a rabeprazole drug, can be used for exploring the metabolic process of the drug in organisms and has a great application research value in clinical pharmacokinetic research.

The invention provides a cephalotaxine derivative. The cephalotaxine derivative has a structure as shown in a formula I or a pharmaceutically acceptable salt or stereoisomer of the cephalotaxine derivative. The cephalotaxine derivative provided by the invention can effectively inhibit the growth of various tumor cells, especially can inhibit Ba/F3-BCR/ABL-T315I mutant cells, is a novel protein synthesis inhibitor capable of overcoming BCR-AblT315I drug-resistant mutation, can be used for preparing anti-tumor drugs, and has a wide market application prospect.

The invention discloses an ABPP-based antitumor drug ginsenoside Rg3 active molecular probe, synthesis and applications thereof, and belongs to the field of chemical biology. According to the presentinvention, the active molecular probe is designed and synthesized through structure modification based on the parent compound Rg3, can achieve the recognition and labeling of the drug action target inliving cells, has antitumor activity similar to Rg3, and provides the advantageous tool in the research on the antitumor action target and the action mechanisms of Rg3.

The invention discloses a compound preparation for treating skin diseases of animals, and a preparation method of the compound preparation for treating skin diseases of animals, relates to the technical field of veterinary medicines, and solves the problem that outdoor applying is inconvenient. The compound preparation comprises the following components in parts by weight: 2 parts of ozone oil, 1.5 parts of olive oil, 1.5 parts of peppermint oil, 2 parts of matrine, 2 parts of camphor, 1 part of borneol, 3 parts of mint, 2 parts of common cnidium fruits, 2 parts of lithargyrum, 2 parts of Chinese galls, 1 part of fructus evodiae, 2 parts of dried ginger and 2 parts of herba violae. The preparation method of the compound preparation comprises the following steps of taking the ozone oil, thecamphor, the olive oil, the peppermint oil, the matrine, the borneol and the dried ginger for standby application; and picking the mint, the common cnidium fruits, the lithargyrum, the Chinese galls,the fructus evodiae and the herba violae, respectively removing impurities, performing thorough cleaning, performing cutting into segments or slices, and performing drying by airing. According to thecompound preparation and the preparation method thereof disclosed by the invention, infected parts of animals are slightly cleaned with a hydrogen peroxide solution and wiped and dried or not scoured, the compound preparation is applied and sprayed onto the infected parts of the animals, and the compound preparation is simple to prepare and convenient to use.

The invention discloses a method for extracting quercetin from semen plantaginis, and belongs to the technical field of quercetin extraction. The method comprises the following steps: (1) coarsely crushing fresh semen plantaginis, then putting the crushed semen plantaginis into a sieve basket, integrally immersing the sieve basket into liquid nitrogen, treating, and repeating the steps 2-3 times;(2) drying the semen plantaginis in the step (1) at low temperature, and crushing to obtain semen plantaginis powder; (3) extracting the semen plantaginis powder by adopting a supercritical CO2 extraction method; and (4) allowing CO2 containing the extract to flow out of the extraction kettle, allowing the CO2 to enter a separation kettle, and carrying out reduced pressure separation to obtain thesemen plantaginis quercetin. According to the method for extracting quercetin from semen plantaginis, the loss of quercetin in the extraction process of semen plantaginis is prevented from being considered, and the quality and the yield of quercetin extracted from semen plantaginis are improved.

The invention discloses a synthesis method of substituted isoindoline, which comprises the following steps: reacting Boc-protected isoindolinone with a Grignard reagent or a metal lithium reagent to obtain an intermediate of ketone or hemiacetal, and reducing ketone or hemiacetal to obtain an intermediate of alcohol, finally, conducting hydroxyl activation to form an easily-leaving group, furtherconducting ring closing under the mild condition, so as to obtain substituted isoindoline. The method is simple and convenient to operate, and can realize rapid preparation in laboratories.

Retro-aldol processes are disclosed that use very low concentrations of retro-aldol catalyst in combination with hydrogenation catalyst of certain activities, sizes and spatial dispersions to obtain the high selectivities to ethylene glycol.